Adaptogens: natural allies for balance and resilience

Antonio Valenzuela Canovaca
Mujer de espalda, close up en su cabeza. Está  leyendo e la mesa de una casa

We live in an age where stress seems to have become the background noise of our lives. Endless days, information overload, lack of rest, and a constant feeling of being in a hurry. In this context, adaptogens have attracted enormous interest due to their ability to help the body better adapt to the physical and emotional demands of daily life.

But what exactly are adaptogens, and why have they become one of the most studied natural supplements in recent years?

What are adaptogens?

There are plants that not only survive but thrive in extreme conditions. They grow in hostile climates, withstand sudden temperature changes, and continue to develop without losing their balance. Adaptogens take their name precisely from this adaptive capacity.

Far from acting as aggressive stimulants or sedatives, adaptogens help the body respond more efficiently to physical, mental, and emotional stress. Their function is not to force a reaction but to promote balance.

We could say they are true harmonizers of the nervous system: they help cushion excesses, promote resilience, and foster a more stable and sustainable energy.

A little history

The term "adaptogen" was coined in 1947 by Soviet scientist Nikolai Lazarev. His goal was to find substances capable of increasing the body's resistance to stress without causing dependence or significant side effects.

His research led to the study of plants such as rhodiola, eleuthero, and schisandra, which were later used by elite athletes, soldiers, and even Soviet cosmonauts.

Decades later, researchers like Alexander Panossian delved into the mechanisms of action of these plants. Their work demonstrated that adaptogens help improve the body's adaptive capacity, promote homeostasis, and have an excellent safety profile.

Adaptogens and the nervous system: how do they work?

Although each adaptogen has its own characteristics, most share the ability to act on some of the body's main regulatory systems:

Autonomic nervous system

Adaptogens help reduce sympathetic hyperactivation associated with chronic stress and promote better parasympathetic regulation, which is related to recovery, rest, and regeneration.

HPA axis (hypothalamic-pituitary-adrenal)

This axis coordinates much of our stress response. Many adaptogens help modulate cortisol production, preventing both excesses and sustained maladaptive responses over time.

Gut-brain axis

Some adaptogens also exert positive effects on the gut microbiota and the bidirectional communication between the gut and the brain, indirectly influencing mood, energy, and cognitive function.

Additionally, numerous studies show that they can contribute to reducing systemic inflammation, neuroinflammation, and oxidative stress.

The most commonly used adaptogens

Ashwagandha (Withania somnifera)

Probably the most popular adaptogen today. It helps balance the stress axis, promotes restorative sleep, and contributes to reducing high cortisol levels.

It is especially beneficial in situations of chronic stress, anxiety, mental exhaustion, or difficulty sleeping.


Rhodiola (Rhodiola rosea)

Known for improving physical and mental energy without causing overstimulation. Traditionally used to increase resistance to fatigue and improve performance in demanding situations.

It can be especially useful during periods of cognitive overload, lack of concentration, or feelings of exhaustion.

Typical dose: 200-400 mg daily of extract.

Reishi (Ganoderma lucidum)

The famous "longevity mushroom" stands out for its ability to modulate the immune system and promote a state of calm and relaxation.

It is an excellent choice for those looking to support both stress management and immune health.

Schisandra (Schisandra chinensis)

A plant used for centuries in traditional Chinese medicine. It has antioxidant properties, promotes physical endurance, and contributes to emotional balance.

It is also valued for its protective action on the liver.

Eleuthero (Eleutherococcus senticosus)

Popularly known as Siberian ginseng, it helps increase physical and mental endurance and promotes better recovery from exertion.

For decades, it was one of the most used adaptogens in Soviet training programs.

Lion's Mane (Hericium erinaceus)

This medicinal mushroom holds a special place due to its effects on brain health. It promotes neuronal plasticity, nerve regeneration, and mental clarity.

Additionally, it can contribute to maintaining good digestive health.

Cordyceps (Cordyceps sinensis and Cordyceps militaris)

Known as the energy mushroom, cordyceps is highly valued for its ability to boost vitality and physical and mental stamina. Its main active compound, cordycepin, promotes the production of ATP—the energy source for our cells—which can help improve performance, combat fatigue, and maintain good cognitive function.

Additionally, it possesses immunomodulatory and neuroprotective properties.


Asian Ginseng (Panax ginseng)

One of the most important tonics in traditional Chinese medicine. It helps improve vitality, physical and mental endurance, and the ability to adapt to stress.

Its active compounds, ginsenosides, have been widely studied for their antioxidant and neuroprotective effects.


The power of synergies

In nature, nothing acts in isolation. Similarly, some adaptogens show complementary effects when properly combined.

For example, a formula combining ashwagandha and rhodiola can help balance both stress and mental energy. Likewise, the combination of lion's mane and reishi is particularly interesting for supporting cognitive function and emotional regulation.

These synergies allow for broader benefits using moderate doses of each ingredient.

Common mistakes when taking adaptogens

Although they are safe supplements, there are some common mistakes to avoid:

  • Taking them without a clear objective.

  • Expecting immediate results.

  • Increasing doses thinking more is better.

  • Ignoring possible interactions with medications or pre-existing conditions.

Tips for choosing an adaptogen

If you are considering incorporating adaptogens into your routine, these recommendations can help:

  • Prioritize formulas that combine several adaptogens. Combining adaptogenic plants and mushrooms allows for acting on different areas simultaneously—stress, energy, concentration, recovery, immune system, or rest—while also leveraging their synergistic effects.

  • Start with moderate doses and observe how your body responds.

  • Maintain supplementation for several weeks to assess its benefits, as their effects are usually progressive and cumulative.

  • Consider taking periodic breaks to promote a good adaptive response.

  • Consult a healthcare professional if you are taking medication or have any illnesses.


The key is not to resist more, but to adapt better.

Adaptogens do not seek to push you beyond your limits or hide signs of exhaustion. Their function is to help the body regain its natural adaptive capacity.

Because true energy does not come from forcing the system, but from finding balance. And when the body regains that balance, something as valuable as mental clarity, resilience, and sustainable vitality appears over time.